Sophia N Karagiannis

Our laboratory leads translational research in cancer immunology, focusing understanding B cell antibody responses and immune cells such as macrophages and NK cells in solid tumours. Insights from patient immunity helps us design novel Fc-enhanced antibodies and antibody-drug conjugates (ADCs). We aim to bridge immunotherapy and synthetic biology, advancing antibody design and delivery systems to target solid cancers such as ovarian, breast cancers and melanoma to advance precision treatments.