Helen Chappell

I am interested in micro-environments, especially those found in relation to bacterial infections. Specifically, I look at the extracellular matrix of bacterial biofilms, modelling the molecular structures found there, and then use these models to assess and predict the movement of small molecules (e.g. pharmaceuticals, antimicrobials) through these extracellular spaces. Ultimately, my work can lead to the engineering of pharmaceuticals that can navigate these hostile biofilm environments.