Neil Thomson

My research interrogates the molecular/nanoscale interactions and processing of biomolecular systems with enzymes, focused on two areas. Designer DNA origami direct or resist nuclease digestion to develop them as delivery vehicles for cellular therapy and/or genome engineering. Processing of collagen structures by MMP enzymes in-vitro are investigated as simple models of complex inflammatory biology. The main technique is AFM but we use many other approaches with physical and life scientists.