Panicos Shangaris

Dr Shangaris’ lab investigates how the fetal liver generates blood and immune cells before birth. Using engineering biology, the team recreates fetal haematopoiesis through 3D organoid and organ-on-chip models of the placenta, liver interface. By combining bioengineering, single-cell analysis, and developmental immunology, the lab reveals how maternal signals shape fetal stem-cell fate, driving advances in prenatal diagnostics, cell therapy, and regenerative medicine.